
Products
L-Arginine
Dr. Ann de Wees Allen is a recognized figure in L-arginine research, having held several patents related to its formulation since the early 1990s.
Her work, particularly the CodeBreaker team’s research, led to a high-profile presentation at the United Nations General Assembly in 2009 regarding the role of L-arginine in managing Sickle Cell disease.

About the Product (ProArgi-9)
The primary product associated with her patents is ProArgi-9 (and its later version, ProArgi-9+).
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Safety Profile: The specific "Core Vector" compound used in her formulas holds GRAS (Generally Recognized as Safe) status, a designation used for food additives.
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Unique Formulation: Her patented approach focuses on a low-glycemic delivery system that utilizes plant glycosides. This is intended to help the L-arginine cross the blood-brain barrier more effectively and reduce common side effects like gastrointestinal distress.
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Legal Claims: Under FDA and FTC guidelines, the product was cleared to make 15 specific structure/function claims, including its ability to help produce Nitric Oxide.
Is It "OK" to Use?
Whether this product is right for you depends on your specific health goals and medical history:
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For Sickle Cell Support: The NIH and other researchers have noted that L-arginine can be beneficial for those with sickle cell by increasing nitric oxide metabolites and potentially reducing pain. However, this should always be managed by a hematologist or specialist.
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Quality Assurance: While the product is based on established patents, always verify that the specific batch you purchase is manufactured in a GMP-compliant facility.
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General Precautions: Even a "patented" or "safe" L-arginine product carries the standard contraindications:
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Do not use if you have had a recent heart attack.
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Consult a doctor if you have kidney disease, asthma, or are prone to cold sores.
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Global Nutrition Intelligence Team



